CBDA is the one particular chemical that has been the subject of much research – serotonin. The happy chemical, scientifically known as 5-hydroxytryptamine (also known as 5-HT), is found in the brain, bowels, and blood platelets. Serotonin helps regulate our sleep-wake cycles and our internal clock.
CBDA for Anxiety and Depression
Its deficiency has been linked to various mood disorders, including depression. Read on to know what is CBDA good for.
Reduces stress-induced anxiety-like behavior
One way to reduce the symptoms of stress is by inhibiting the activity of the calcium channel PKCe in the amygdala. This calcium channel is believed to be essential in regulating CRF, the hormone that triggers anxiety. This study shows that inhibition of PKCe reduces stress-induced anxiety-like behavior in rats. In addition, a previous study showed that inhibiting PKCe significantly reduced the symptoms of stress, thereby reducing food intake and energy expenditure.
Reduces nausea
Anxiety and sadness can be effectively treated with cannabis extracts. CBDA is one such example. It is also beneficial in the treatment of sleep disorders. Its benefits have been studied and demonstrated in several clinical trials. However, the side effects of this drug can be significant. There are several ways to reduce the chance of nausea. Over-the-counter medications, dietary modifications, and antihistamines may reduce nausea. However, the side effects can differ from person to person.
Regulates mood
Unlike CBD, CBDA does not appear to bind directly to cannabinoid receptors. Instead, it inhibits the COX-2 enzyme, which is expressed in inflammatory cells. The effect of inhibiting COX-2, along with the other positive impacts of CBDA, is to reduce inflammation and improve mood. CBDA also has a high affinity for serotonin receptors, a substance that helps regulate mood and relieve nausea and vomiting.
Suppresses cancer cell migration
CBDA may help treat MDA-MB-231 breast cancer cells. Researchers published a study in the Journal of Natural Medicine in January 2017 that examined the bioactivity of CBDA. It inhibited the migration of the breast cancer cell line. This cell line has been extensively studied for its role in cancer biology. In addition, CBDA suppresses an enzyme called COX-2, which contributes to the progression of the disease. The study found that CBDA significantly reduced COX-2 levels in the cells after treatment.
Reduces seizures
Studies show that CBDA helps treat anxiolytic seizures in several patients with anxiety disorders. In addition, it has been shown to lower the frequency and severity of convulsions. CBDA is accessible without a prescription, in pill and liquid form. The substance is a natural hemp derivative that is non-addictive. CBDA is entirely safe and has no adverse side effects. A study by researchers at the University of California, San Francisco, determined whether CBDA effectively treats anxiety and depression.
Reduces anxiety
A recent study has shown that hemp-based CBDA products can help with mental health conditions, including anxiety and depression. Among autistic adults, anxiety and depression are common. CBDA acts as an ideal natural anxiolytic, interlocking the webs of 5-HT1A receptors in the brain. This molecule lowers pressure by increasing serotonin levels and decreasing serotonin reabsorption in the brain. Higher serotonin levels increase feelings of happiness.
Reduces depression
Researchers recently discovered that CBDA might help reduce depression and anxiety symptoms. This compound is similar to serotonin, the brain chemical that regulates mood and moderates emotions. However, unlike serotonin, CBDA has a much higher affinity for the 5-HT receptor than serotonin. SSRI drugs, or selective serotonin reuptake inhibitors, which prevent the brain from reabsorbing serotonin, work by causing the brain to maintain higher levels of this neurotransmitter.
